FAQ
Omega 3
Omega 3 is a combination of fatty acids (EPH + DHA) that are essential to our health.
Studies show that low Omega 3 Index results have been linked to higher risk of
cardiovascular disease, inflammation, allergic reactions, migraines, headaches, ADHD
and a variety of poor health outcomes. The good news is that consuming Omega 3
Galilee products can help you quickly, safely, and effectively raise your Omega 3 Index
results!
Omega-3 is an essential fatty acid. Yet, our bodies cannot produce Omega-3 on their
own. The main sources for Omega 3 are fish, especially sardines, anchovies, and
mackerel. There are two forms of Omega-3 fatty acids that are most important to our
health - EPA and DHA. These fatty acids reduce inflammation and blood clotting, and
assist in brain development and proper brain function, among other things. A deficiency
in these fatty acids may become a risk factor for various health conditions such as
cardiovascular diseases, attention deficit disorder (ADD/ADHD), depression, and more.
Finding out if you are deficient is easy - a home testing kit can calculate your Omega-3
blood index (level). You can purchase a testing kit on our website!
Many studies have shown that lack in Omega-3 fatty acids is associated with an
increased risk of cardiovascular diseases 1 , 2 , 3 , a range of attention and concentration
disorders 4 , 5 , 6 , depression and anxiety 7 , 8 , 9 , 10 , dry eye syndrome 11 , migraines 12 and more.
Unfortunately, most of us are deficient in Omega-3, and the average Omega index level
in the population is between one-third and a half of the recommended level 13 . The good
news is that it is easy and convenient to supplement your diet by consuming Omega 3
fish oil capsules.
Studies have established that a deficiency in marine Omega-3 is a risk factor for
attention disorders iv, v, vi . A review of studies published in 2020 vi reinforces the known
connection between Omega-3 deficiency and attention deficit disorder (ADD/ADHD) in
children and adolescents. The review found that children and adolescents with attention
disorders have lower levels of Omega-3 in their bodies. Children and adolescents who
started with low Omega-3 levels in their blood (low Omega-3 index) and received a
significant Omega-3 supplement, which raised their Omega-3 index, showed
improvement in clinical measures of attention disorders and even in depression.
An Israeli study conducted at the "Ziv" Medical Center in Tzfat by Dr. Uri Yitzker and Dr.
Ayelet Omer Armon and published in Current Psychiatry Research and Reviews in 2023
iv , showed that appropriate supplementation of Omega-3, adjusted to body weight, along
with the important addition of Vitamin E, in children with attention disorders significantly
raised their Omega-3 index and led to improvement in attention and hyperactivity
measures. The researchers defined this improvement as "a very significant
improvement."
Omega-3 is especially important for the proper development of the fetus and newborn,
but is also important for preventing premature birth. Since it all rely on the mother’s
Omega-3 stores (which may already be deficient, as is the case for most of the
population), it is recommended for pregnant and breastfeeding women to take an
Omega-3 supplement during pregnancy and breastfeeding. This is also the official
recommendation of ISSFAL (the International Society for the Study of Fatty Acids and
Lipids) 14 and the American pregnancy association. 15
Omega-3 dosage depends on your height, weight, and how deficient you may be. We
offer a dosage calculator that will help you calculate how much Omega-3 you should
consume. If you’ve tested your Omega-3 Index, make sure to include that in your
calculation.
It is recommended to take Omega-3 with a fatty food, such as yellow cheese, butter,
almonds, walnuts, etc. However, it is best not to take it close to red meat (to avoid the
oxidation of Omega-3 inside the body). There is no specific time of day to take your
Omega-3 capsules. To increase absorbency, have your capsules with fatty foods and
avoid having it with red meat.
If you are worried about your child swallowing Omega-3 capsules, you can simply
puncture a capsule, squeeze out the oil, and add it to a smoothie, in a PB&J sandwich,
a glass of milk, or any other snack your kids enjoy.
We don’t sell bottled Omega-3 fish oil because that product is too susceptible to
oxidation. Encapsulating Omega-3 helps us ensure the product remains fresh, safe, and
toxin free.
Omega-3 from fish oil is highly sensitive to heat and humidity. Left unrefrigerated, your
Omega 3 can oxidize, degrading its nutritional value. To ensure you receive and
consume the highest quality product, we maintain a fully refrigerated supply chain, from
the manufacturer to your door. This helps maintain a very low oxidation level and
preserves all the nutritional benefits of our Omega-3.
Yes! We strongly recommend storing Omega-3 in your refrigerator (no need to freeze
your Omega-3). But don’t fret - despite the importance of refrigeration, Omega-3 has a
safety margin of up to 3 weeks with no refrigeration. So, if you forgot your Omega 3
Galili on the counter overnight, simply return it to the fridge the next morning.
Omega-3 from marine sources (that is, from fish) contain both EPA + DHA. In contrast,
plant-based Omega-3 (ALA) requires our body to take on an additional conversion
process before EPA + DHA become readily available for digestion. That makes for a far
less efficient process.
Just like fresh fish kept outside the refrigerator, Omega-3 fish oil capsules can spoil (that
is, oxidize). When Omega-3 oxidizes, its effectiveness decreases, and harmful oxidation
byproducts are formed. Consuming oxidized Omega-3 fish oil capsules can actually be
harmful to your health. That’s why our capsules are kept refrigerated throughout the
supply chain. We don’t keep fresh fish sitting on the kitchen counter – the same is true
of Omega-3 capsules!
TOTOX (meaning “total oxidation”), is the international standard for Omega-3 oxidation.
Safe TOTOX levels should not exceed 26. The TOTOX value does not start at zero and
naturally increases over time. However, the important thing is ensuring that throughout
the product's shelf life, this value does not exceed 26. Above this threshold, Omega-3 is
considered oxidized to a level that may not be sufficiently safe for consumption.
Omega 3 Galil guarantees that our Omega-3 capsules do not exceed this threshold,
unlike other products sold on the shelf, which often exceed a TOTOX value of 26 even
before the product's expiration date, even In the U.S. We lab test every batch of our
capsules and provide you with a quality assurance certificate, so you know the product
is safe.
The two biologically active Omega-3 fatty acids are EPA and DHA; the ratio between
the two is the “Omega-3 composition”. The EPA:DHA ratio is very important - we
recommend double the amount of EPA to DHA in each capsule. High ratios of EPA to
DHA have been observed in studies and guidelines from international organizations on
a variety of health conditions i, v, iiiiv, vi, vii such as the International Society for Nutritional
Psychiatry 16 . The reason is that EPA is crucial for regulating inflammatory processes
through the production of local hormones (eicosanoids). It has a shorter half-life and is
quickly utilized in dynamic processes like inflammation control. The body requires more
EPA to maintain a balance between pro-inflammatory and anti-inflammatory responses,
not only in chronic diseases but also in psychiatric conditions.
i Bhatt, D. L., Steg, P. G., Miller, M., Brinton, E. A., Jacobson, T. A., Ketchum, S. B., Doyle, R. T., Jr, Juliano, R. A.,
Jiao, L., Granowitz, C., Tardif, J. C., Ballantyne, C. M., & REDUCE-IT Investigators (2019). Cardiovascular Risk
Reduction with Icosapent Ethyl for Hypertriglyceridemia. The New England journal of medicine, 380(1), 11–22.
https://doi.org/10.1056/NEJMoa1812792
ii Welty, F. K., Schulte, F., Alfaddagh, A., Elajami, T. K., Bistrian, B. R., & Hardt, M. (2021). Regression of human
coronary artery plaque is associated with a high ratio of (18-hydroxy-eicosapentaenoic acid + resolvin E1) to
leukotriene B 4 . FASEB journal : official publication of the Federation of American Societies for Experimental
Biology, 35(4), e21448.
https://doi.org/10.1096/fj.202002471R
iii von Schacky, C., Kuipers, R. S., Pijl, H., Muskiet, F. A. J., & Grobbee, D. E. (2023). Omega-3 fatty acids in heart
disease-why accurately measured levels matter. Netherlands heart journal : monthly journal of the Netherlands
Society of Cardiology and the Netherlands Heart Foundation, 31(11), 415–423.
https://doi.org/10.1007/s12471-023-01759-2
iv Yatzkar Uri, Amir Eti, Tamir Snait and Armon-Omer Ayelet*, Omega-3 Fatty Acid Supplementation Improves
Attention Deficit-Hyperactivity Disorder Symptoms in Children, Current Psychiatry Research and Reviews 2023; (19).
v Chang, J. P., Su, K. P., Mondelli, V., & Pariante, C. M. (2018). Omega-3 Polyunsaturated Fatty Acids in Youths with
Attention Deficit Hyperactivity Disorder: a Systematic Review and Meta-Analysis of Clinical Trials and Biological
Studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
43(3), 534–545.
https://doi.org/10.1038/npp.2017.160
vi van der Wurff, I. S. M., Meyer, B. J., & de Groot, R. H. M. (2020). Effect of Omega-3 Long Chain Polyunsaturated
Fatty Acids (n-3 LCPUFA) Supplementation on Cognition in Children and Adolescents: A Systematic Literature
Review with a Focus on n-3 LCPUFA Blood Values and Dose of DHA and EPA. Nutrients, 12(10), 3115.
https://doi.org/10.3390/nu12103115
vii Kelaiditis, C. F., Gibson, E. L., & Dyall, S. C. (2023). Effects of long-chain omega-3 polyunsaturated fatty acids on
reducing anxiety and/or depression in adults; A systematic review and meta-analysis of randomised controlled
trials. Prostaglandins, leukotrienes, and essential fatty acids, 192, 102572.
https://doi.org/10.1016/j.plefa.2023.102572
viii Antao, H. S., Sacadura-Leite, E., Bandarra, N. M., & Figueira, M. L. (2023). Omega-3 index as risk factor in
psychiatric diseases: a narrative review. Frontiers in psychiatry, 14, 1200403.
https://doi.org/10.3389/fpsyt.2023.1200403
ix Kiecolt-Glaser, J. K., Belury, M. A., Andridge, R., Malarkey, W. B., & Glaser, R. (2011). Omega-3 supplementation
lowers inflammation and anxiety in medical students: a randomized controlled trial. Brain, behavior, and
immunity, 25(8), 1725–1734.
https://doi.org/10.1016/j.bbi.2011.07.229
x Osuna, E., Herter-Aeberli, I., Probst, S., Emery, S., Albermann, M., Baumgartner, N., Strumberger, M., Ricci, C.,
Schmeck, K., Walitza, S., Hersberger, M., Zimmermann, M. B., Häberling, I., Berger, G., Baumgartner, J., & Omega-3
study team (2023). Associations of n-3 polyunsaturated fatty acid status and intake with paediatric major depressive
disorder in Swiss adolescents: A case-control study. Journal of affective disorders, 339, 355–365.
https://doi.org/10.1016/j.jad.2023.07.046
xi Bhargava, R., Pandey, K., Ranjan, S., Mehta, B., & Malik, A. (2023). Omega-3 fatty acids supplements for dry eye -
Are they effective or ineffective?. Indian journal of ophthalmology, 71(4), 1619–1625.
https://doi.org/10.4103/IJO.IJO_2789_22
xii Wang, H. F., Liu, W. C., Zailani, H., Yang, C. C., Chen, T. B., Chang, C. M., Tsai, I. J., Yang, C. P., & Su, K. P.
(2024). A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
Brain, behavior, and immunity, 118, 459–467.
https://doi.org/10.1016/j.bbi.2024.03.019
xiii Schuchardt, J. P., Beinhorn, P., Hu, X. F., Chan, H. M., Roke, K., Bernasconi, A., Hahn, A., Sala-Vila, A., Stark, K.
D., & Harris, W. S. (2024). Omega-3 world map: 2024 update. Progress in lipid research, 95, 101286.
https://doi.org/10.1016/j.plipres.2024.101286
xiv Best, K. P., Gibson, R. A., & Makrides, M. (2022). ISSFAL statement number 7 - Omega-3 fatty acids during
pregnancy to reduce preterm birth. Prostaglandins, leukotrienes, and essential fatty acids, 186, 102495.
https://doi.org/10.1016/j.plefa.2022.102495
xv https://americanpregnancy.org/healthy-pregnancy
xvi Guu, T. W., Mischoulon, D., Sarris, J., Hibbeln, J., McNamara, R. K., Hamazaki, K., Freeman, M. P., Maes, M.,
Matsuoka, Y. J., Belmaker, R. H., Jacka, F., Pariante, C., Berk, M., Marx, W., & Su, K. P. (2019). International Society
for Nutritional Psychiatry Research Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major
Depressive Disorder. Psychotherapy and psychosomatics, 88(5), 263–273.
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